NIH Funding Opportunities

Explore the latest NIH funding opportunities at the intersection of health and extreme weather.

This list highlights programs relevant to the CAFE community of practice, helping researchers identify resources to advance their work and foster cross-disciplinary collaboration.

R25 Education Program

The NIH Program on Health and Extreme Weather (HEW) offers three new funding opportunities related to training and education.

‍Under NIH’s new preferred funding structure, the HEW initiative and its participating Institutes, Centers, and Offices may consider R25 applications that fall within the scope of the HEW Highlighted Topic published in May 2026. That Highlighted Topic states:

“Methods to advance the aggregation, linking, accessibility, and interpretation of health and weather-related data are also of interest, as are efforts to provide training and build the capacity of researchers across the disciplines needed to address the health impacts of extreme weather. Community engagement, interdisciplinary collaboration, and research translation are encouraged in health and extreme weather research applications.”

Please reach out to the Scientific Contact on the Highlighted Topic if you are interested in applying and any have questions.

• NIH Research Education Program - Research Experiences (Parent R25 - Clinical Trial Not Allowed) PA-27-036
  
• NIH Research Educational Program - Mentoring Activities & Networks (Parent R25/UE5 - Clinical Trial Not Allowed) PA-27-035
  
• NIH Research Education Program - Courses, Curriculum and Methods (Parent R25 - Clinical Trial Not Allowed) PA-27-034

FY27 NIH Director’s Awards

The NIH’s High-Risk, High-Reward Research program offers four funding opportunities for the FY27 NIH Director’s Awards:

• NIH Director's New Innovator Award (DP2 - Clinical Trial Optional): RFA-RM-27-002
  Supports early-stage investigators who propose bold and highly innovative research ideas with the potential for broad impact. Learn more. Questions: NewInnovatorAwards@mail.nih.gov. Deadline: August 17.
  
  
• NIH Director’s Transformative Research Award (R01 - Clinical Trial Optional): RFA RM-27-003  
  Supports individuals or teams proposing remarkably innovative and/or unconventional research projects with the potential to create or overturn fundamental paradigms. Learn more. Questions: Transformative_Awards@mail.nih.gov. Deadline: September 3.
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• NIH Director's Pioneer Award (DP1 - Clinical Trial Optional): RFA-RM-27-001  
  Supports individual scientists at any career stage with outstanding records of creativity who propose pioneering approaches to address major challenges in biomedical and behavioral research.  Learn more. Questions: PioneerAwards@mail.nih.gov. Deadline: September 9.
  
  
• NIH Director’s Early Independence Award (DP5 - Clinical Trial Optional): RFA RM-27-004Enables rigorous and promising early career investigators to bypass the traditional postdoctoral training period and launch an independent research career. Learn more. Questions?  EarlyIndependence@od.nih.gov. Deadline: September 10. 

Institutional Career Development Awards (K12)

• NIEHS is a participating institute with an interest in "proposals that provide new pediatric healthcare providers, obstetricians and gynecologists, and other healthcare professionals with environmental health training that blends research, research translation, and practice-based applications to prepare them as independent researchers and recognized leaders." Read the parent announcement and find details about the interests of each participating institute/center. Questions: NOFO.Information@niehs.nih.gov, cc: Liam O’Fallon, Mike Humble, and Jennifer Collins.

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To explore all currently active NIH funding opportunities, please visit https://grants.nih.gov/funding/explore-nih-opportunities.

Funding Forecasts

NIEHS intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications in the areas below. Estimated post date: November 27, 2026. Estimated application due date: January 29, 2027.

• ‍Health and Extreme Weather (HEW) Research Coordination and Data Center (U2C - Clinical Trial Not Allowed)
  Will solicit applications for research coordination and data support for the Health and Extreme Weather (HEW) initiative including two closely aligned components: research coordination and data support. The coordinating component will facilitate engagement across the initiative’s grantees and the larger HEW community of practice. The data component will develop resources and infrastructure to facilitate access to and use of health and environmental data. Learn more.
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• Health and Extreme Weather Solutions-Focused Research Hubs (U54 - Clinical Trial Optional)
  Will solicit applications that propose translational research hubs with multiple highly integrated components focused on research, capacity building, and community/public health translation for regionally relevant topics related to the health impacts of extreme weather and cumulative exposures, including but not limited to wildfire smoke, extreme heat, flooding, hurricanes, drought, and other climate-related hazards affecting populations at heightened risk across the lifespan. Learn more.